Magainin 2 and PGLa are antimicrobial peptides found together in frog Media Shelf skin secretions.When added as a mixture they show an order of magnitude increase in antibacterial activity and in model membrane permeation assays.Here we demonstrate that both peptides can form fibers with beta-sheet/turn signature in ATR-FTIR- and CD-spectroscopic a
The purpose of this article is to describe lessons from the first lymphoma clinical trial conducted by the AIDS Malignancy Consortium (AMC) in sub-Saharan Africa (SSA).AMC-068 was a randomized phase II comparison of intravenous versus oral chemotherapy for HIV-positive diffuse large B-cell lymphoma.Opening in 2016, AMC-068 planned to enroll 90 pati
Abstract Background Numerous studies have demonstrated that long non-coding Ski de fond - Accessoires - Fixations - Skate RNAs are related to plenty of human diseases.Therefore, it is crucial to predict potential lncRNA-disease associations for disease prognosis, diagnosis and therapy.Dozens of machine learning and deep learning algorithms have bee
In the context of the mixed perception among scholars whether the Mahabharat is a pacifist or a militant text, this paper analyzes the rhetorical project of the epic to examine its position on violence.Highlighting the existence of two main arguments in the Mahabharat, this paper argues that the author has crafted a grand rhetorical project to ques
Colorectal cancer (CRC) is rapidly increasing representing the second Insulated Bottle Holder most frequent cause of cancer-related deaths.From a clinical-molecular standpoint the therapeutically management of CRC focuses on main alterations found in the RAS family protein, where single mutations of KRAS are considered both the hallmark and the tar